Biosynthesis of Selenium Nanoparticles and Evaluation of Its Antibacterial Activity against Pseudomonas aeruginosa

نویسندگان

چکیده

Background. A fundamental component of innate immunity is represented by skin that acts as a first aid against infection. The skin’s epithelial barriers, respiratory tract, and eyes directly contacting with the external environment have incremented probability opportunistic pathogen Pseudomonas aeruginosa causes various infections in immunocompromised hosts. In addition, one-third P. clinical isolates are resistant to three or more antibiotics. Lately, lots researchers concentrate on halophilic microorganisms due affordable novel biomolecules. One these biomolecules metal nanoparticles. MNPs exhibited antimicrobial functionality variety microbes. Amidst MNPs, SeNPs one most extensively studied. this study, bacteria from solar saltern were employed for biosynthesis SeNPs. Aim. This study aimed evaluate antibacterial properties which synthesized microorganisms. Result. NPs Halomonas eurihalina intracellularly. produced identified through assays such UV-Vis spectroscopy, XRD, DLS, FTIR, SEM. spectroscopy confirmed presence average particle size was 260 nm. FTIR capping agent inhibit aggregation Also, selenium nanoparticles natural crystalline nature verified XRD. SEM also revealed spherical shape. Furthermore, significant activity aeruginosa. Conclusion. According obtained result, biosynthesized demonstrated remarkable characteristics make them profitable nonantibiotics decrease morbidity mortality associated tissue infections.

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ژورنال

عنوان ژورنال: Advances in Materials Science and Engineering

سال: 2022

ISSN: ['1687-8434', '1687-8442']

DOI: https://doi.org/10.1155/2022/4118048